Longitudedx
Understanding Changes in Health Over Time
Everyone’s health changes over time. To understand and predict these changes, we are building a library of personal biomarker timelines to track wellness and disease through time at the molecular level, and applying machine learning strategies to model personal health for the benefit of our users.
Provide users with kits to collect tiny blood samples on a regular basis (quick, simple, convenient)
Read out the body’s internal sensors by measuring established biomarkers in the samples
Establish each user’s personal baselines and biomarker trajectories
Connect biomarker changes with external events, health trends, treatments, etc.
Understanding the responses to health events over time
Improving the evaluation of treatments in clinical trials
Building personalized AI health models to guide health decisions
Multiple measurements of the same proteins over time provides accurate “normal” baselines for each biomarker in each user
This allows us to focus on changes, large and small, from personal baselines
Correlation among biomarkers and with external events exposes a rich new source of health data
Simple, convenient, inexpensive, and as painless as possible
We know because we’ve been collecting dried blood samples from ourselves for more than 10 years, accumulating improvements
Our approach is designed to take 2 minutes start to finish, and uses smartphone features to record context
Each 4-page Sample Diary booklet holds 32 samples – a month of daily samples
By consistently tracking your biomarkers over time with daily entries in the SampleDiary, we can establish your personal baselines and easily see small variations over time. Daily sampling provides a much higher resolution picture of health, and reveals events that are unobserved by conventional infrequent sample collection.
LongitudeDX is transforming the established, previously expensive menu of clinical protein blood tests into an economical, personalized health monitoring tool
The test menu being created covers a majority of clinically-tested blood proteins used in medicine today as well as validated next-generation biomarkers
LongitudeDX uses patented SISCAPA technology to measure many proteins at the same time in tiny dried blood samples with ultra-high specificity, high precision and low cost
SISCAPA is based on the gold standard for protein quantitation (peptide mass spectrometry), and employs proprietary data normalization methods
